The 7 Best Detox Centers in Mississippi

Finding the right detox center in Mississippi is often the most urgent first step in addiction recovery. Detoxification — the process of safely clearing drugs or alcohol from the body under clinical supervision — is medically necessary for anyone with physical dependence on alcohol, opioids, or benzodiazepines. This guide covers seven of the best detox programs serving Mississippi, from the top private facility in the state to Medicaid-funded and state-certified programs accessible to anyone who needs help.

Important note: Oxford Treatment Center accepts most major private insurance plans but does not accept Medicaid or Medicare. The other programs listed below are nonprofit, state-operated, or government-funded facilities that accept Medicaid or state-financed insurance.

Quick Comparison: 7 Best Detox Centers in Mississippi

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1. Oxford Treatment Center – Best Overall Detox Center in Mississippi

Location: 297 County Road 244, Etta, MS 38627 (northern Mississippi, approx. 90 minutes from Memphis)
Best for: Adults seeking hospital-based medical detox followed by comprehensive inpatient residential treatment in Mississippi
Payment: Private insurance, self-pay, financing available; does not accept Medicaid or Medicare

Oxford Treatment Center is Mississippi’s premier private addiction treatment facility, set on more than 100 acres of wooded, rolling hills within the Holly Springs National Forest. Operated by American Addiction Centers (AAC), Oxford provides hospital-based medical detox with 24/7 physician and nursing oversight — the highest standard of clinical care available for managing withdrawal from alcohol, opioids, benzodiazepines, and other substances. Oxford’s 24-bed dedicated detox unit is staffed by board-certified addiction medicine physicians and nurses around the clock, ensuring that withdrawal complications are identified and managed in real time.

Unlike many programs that separate detox from treatment, Oxford provides integrated care from admission through discharge — patients who complete detox transition directly into the residential program on the same campus, eliminating the gap where relapse most commonly occurs. The Joint Commission-accredited facility holds an A+ rating with the Better Business Bureau and is in-network with Aetna, Cigna, Humana, Ambetter, and other major commercial insurers.

Why Oxford stands apart:

• Hospital-based medical detox unit with 24/7 physician and nursing coverage
• Integrated detox-to-residential transition on the same 110-acre campus
• Medical detox for alcohol, opioids (including fentanyl and heroin), benzodiazepines, and stimulants
• MAT (buprenorphine, naltrexone) initiated during detox when clinically appropriate
• Dual diagnosis evaluation and psychiatric stabilization during detox
• Equine therapy, fitness facilities, and private lake on the residential campus
• Salute to Recovery program for veterans and first responders
• 90-Day Brand Promise: complete 90 days of recommended treatment and if relapse occurs, return for 30 days at no additional cost

Verify your insurance at Oxford Treatment → or call 662-638-0015

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2. Communicare Haven House – Best Medicaid-Funded Detox Near Oxford, Mississippi

Location: 152-A Highway 7 South, Oxford, MS 38655
Best for: Adults in northern Mississippi needing medical detox and residential treatment under Medicaid
Payment: Medicaid, Medicare, TRICARE, private insurance, sliding scale; no one turned away for inability to pay

Communicare Haven House is a 48-bed residential and detox program in Oxford, Mississippi, operated by Communicare of Mississippi — the state-designated Community Mental Health Center for Lafayette, Calhoun, Marshall, Panola, Tate, and Yalobusha counties. As a local government healthcare organization certified by the Mississippi Department of Mental Health, Haven House accepts Medicaid and operates on a sliding fee scale at 200% or below the federal poverty threshold, ensuring no one is turned away for inability to pay.

Haven House provides medical detox for alcohol, opioids, benzodiazepines, cocaine, and methamphetamine, integrated with inpatient residential treatment for adults. MAT options including buprenorphine (Suboxone) and naltrexone are available. The program is CARF-accredited and takes a holistic approach that incorporates yoga, meditation, art therapy, music therapy, and time in nature alongside evidence-based CBT and DBT. Family therapy is also offered.

Key services:

• Medical detox for alcohol, opioids, benzos, cocaine, and methamphetamine
• 48-bed inpatient residential treatment for adults
• MAT: buprenorphine (Suboxone) and naltrexone
• Co-occurring disorder (dual diagnosis) treatment
• Holistic programming: yoga, meditation, art and music therapy, nature-based activities
• CARF-accredited; Mississippi DMH-certified; sliding scale for uninsured

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3. Pine Grove Behavioral Health and Addiction Services – Best Full-Service Medicaid Detox in South Mississippi

Location: 2255 Broadway Drive, Hattiesburg, MS 39402
Best for: Adults statewide needing hospital inpatient detox and comprehensive residential or outpatient treatment under Medicaid
Payment: Medicaid, Medicare, TRICARE, most major private insurance

Pine Grove Behavioral Health and Addiction Services, an extension of Forrest General Hospital, is Mississippi’s largest behavioral health and addiction treatment center — a nationally recognized program that has treated patients from all 82 Mississippi counties, all 50 states, and several foreign countries since 1984. Pine Grove provides hospital inpatient detoxification for alcohol, opioids, benzodiazepines, and other substances, with 24/7 access to medical professionals throughout the withdrawal process. Inpatient detox is available for patients entering Pine Grove’s residential programs.

Pine Grove accepts Medicaid, Medicare, and most major private insurance, making it one of the most accessible high-quality detox options in Mississippi for patients across all payment situations. The facility is CARF-accredited, holds NAATP membership, and offers gender-specific residential programs, dual diagnosis treatment, and a specialized track for co-occurring eating disorders alongside addiction.

Key services:

• Hospital inpatient detox with 24/7 medical access
• Gender-specific residential programs: Men’s Next Step, Women’s Center, and Legacy programs
• MAT for opioid and alcohol use disorder
• Dual diagnosis treatment for addiction and co-occurring psychiatric conditions
• Outpatient programs and aftercare through multiple South Mississippi locations
• CARF-accredited; accepts Medicaid, Medicare, and TRICARE

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4. Clearview Recovery Center – Best Medicaid-Funded Residential Detox and Rehab in South-Central Mississippi

Location: 3 Clearview Circle, Moselle, MS 39459 (Jones County, near Hattiesburg)
Best for: Adults needing Medicaid-covered residential detox assessment and 30-to-60-day residential treatment in South Mississippi
Payment: Medicaid, private insurance, sliding scale

Clearview Recovery Center is a CARF-accredited residential addiction treatment program operated by Pine Belt Mental Healthcare Resources — the DMH-certified Community Mental Health Center for the Pine Belt region. Located in the pines of Moselle, Mississippi, Clearview provides 54-bed co-ed residential treatment with a clinical assessment on admission to determine whether medical detox is required before entering the program. The primary program is a 30-day residential stay rooted in the 12-step model; an extended program deepens that work for an additional 30 days.

Clearview accepts Medicaid and is certified by the Mississippi Department of Mental Health. A contracted psychiatrist and nurse practitioner provide integrated dual diagnosis psychiatric care alongside addiction treatment. IOP step-down services are available for clients transitioning back to the community.

Key services:

• Clinical assessment on admission to determine detox need
• 54-bed residential SUD treatment (30-day primary + 30-day extended programs)
• Co-occurring disorder (dual diagnosis) treatment with contracted psychiatrist
• IOP step-down and transitional sober living
• CARF-accredited; Mississippi DMH-certified
• Medicaid accepted; sliding scale for uninsured

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5. Region IV Mental Health Services – Best Medicaid-Funded Detox and SUD Services in Northern Mississippi

Location: Headquarters: 2100 East Chambers Drive, Booneville, MS (plus offices in Corinth, Hernando, Ripley, and Iuka)
Best for: Adults in Alcorn, DeSoto, Prentiss, Tippah, and Tishomingo counties needing detox access and outpatient or residential SUD care under Medicaid
Payment: Medicaid, Medicare, TRICARE, state-funded, sliding scale

Region IV Mental Health Services is the DMH-certified Community Mental Health Center for northern Mississippi, serving five counties from headquarters in Booneville with additional offices across the region. Founded in 1972, Region IV is a nonprofit and Federally Qualified Health Center that provides chemical dependency services including detox, inpatient rehabilitation, outpatient treatment, IOP, partial hospitalization, MAT, crisis stabilization, and sober living — accepting Medicaid, Medicare, TRICARE, and a sliding scale for uninsured patients.

Region IV is the primary public-access addiction treatment gateway for northern Mississippi residents, and as a FQHC it does not turn away patients based on inability to pay. Mobile Crisis Response Teams are available 24/7 across all five counties for individuals in immediate addiction or mental health crises.

Key services:

• Detox services and withdrawal management
• Inpatient rehabilitation and outpatient SUD treatment
• MAT including buprenorphine and naltrexone
• Crisis stabilization and 24/7 mobile crisis response
• Co-occurring disorder treatment
• Federally Qualified Health Center: does not turn away patients for inability to pay

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6. East Mississippi State Hospital – Substance Use Disorder Unit – Best State-Operated Inpatient Detox for Men in Mississippi

Location: Meridian, MS (Lauderdale County)
Best for: Adult men requiring state-funded inpatient SUD treatment and detox, including those admitted through voluntary or court-ordered processes
Payment: State-funded (Mississippi DMH), Medicaid; voluntary and involuntary admission pathways

East Mississippi State Hospital (EMSH) is a Mississippi Department of Mental Health-operated behavioral health program providing inpatient SUD treatment — including detox — for adult men. As a state-operated facility, EMSH is the public safety net for men with severe substance use disorders who require a level of medical or psychiatric intensity that community programs cannot provide. The facility accepts Medicaid and receives direct state funding through DMH.

Admission to EMSH for SUD treatment is typically coordinated through the local Community Mental Health Center after a clinical assessment determines that inpatient state hospital-level care is needed. Mississippi State Hospital in Rankin County serves women under an equivalent program. The DMH Helpline (1-877-210-8513) provides 24/7 guidance on accessing state hospital services.

Key services:

• State-operated inpatient SUD treatment with detox capability (adult men)
• Acute care for severe substance use disorders and co-occurring psychiatric conditions
• Voluntary and court-ordered (involuntary) admission pathways
• Medicaid accepted; state-funded for those who qualify
• Coordinated through local Community Mental Health Center referrals
• 24/7 DMH Helpline access: 1-877-210-8513

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7. Mississippi DMH – Community Mental Health Center Network – Best Statewide Gateway to Detox and SUD Services in Mississippi

Location: Statewide — 14 regional Community Mental Health Centers serving all 82 Mississippi counties
Best for: Any Mississippi resident needing access to publicly funded detox, withdrawal management, residential treatment, or outpatient SUD care
Payment: Medicaid, state-funded, sliding scale; DMH Helpline 1-877-210-8513

The Mississippi Department of Mental Health (DMH) administers the state’s public addiction treatment system through a network of 14 regional Community Mental Health Centers (CMHCs) covering all 82 counties. CMHCs are the primary entry point for Medicaid members and uninsured Mississippi residents who need withdrawal management, outpatient SUD treatment, residential care, or referral to higher levels of care including state hospital SUD units. All DMH-certified providers follow ASAM Criteria for level-of-care placement.

Services available across the CMHC network include outpatient treatment, intensive outpatient (9–19 hours/week), withdrawal management (detox), residential treatment, MAT, and recovery support services. Priority access is given to pregnant women, IV drug users, and individuals at highest risk. The DMH Helpline (1-877-210-8513) is available 24/7 to connect Mississippi residents to services and provide referrals to the nearest appropriate provider.

Key services:

• 14 regional CMHCs covering all 82 Mississippi counties
• Withdrawal management (detox), outpatient, IOP, residential, MAT, and recovery support
• Medicaid accepted; sliding scale for uninsured; no one turned away
• Priority admission for pregnant women and IV drug users
• 24/7 Mobile Crisis Response Teams available in every county
• DMH Helpline: 1-877-210-8513 (24/7) for referral and crisis support

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How to Choose the Right Detox Center in Mississippi

Choosing a detox center starts with matching the level of clinical intensity to your specific situation. Key factors to consider:

• Medical supervision is essential for alcohol, benzodiazepine, and severe opioid withdrawal. Alcohol and benzodiazepine withdrawal can be fatal without physician oversight and seizure-prevention medication. Oxford Treatment Center and Pine Grove both provide hospital-level medical detox. For Medicaid members, Communicare Haven House and the CMHC network provide access to medically appropriate withdrawal management.
• Detox is not treatment. Detox clears the body of substances but does not address the behavioral, psychological, and social dimensions of addiction. NIDA and SAMHSA both recommend transitioning directly from detox into a residential or intensive outpatient program. All seven programs above include or coordinate post-detox treatment.
• Insurance and payment. If you have private insurance, Oxford Treatment Center offers the highest level of medical detox in Mississippi with seamless residential follow-up on the same campus. If you have Medicaid or no insurance, Communicare Haven House (northern MS), Pine Grove (southern MS), and the DMH CMHC network (statewide) are strong options.
• Geographic access. Mississippi’s treatment resources are distributed across the state. Northern Mississippi residents have strong options at Oxford Treatment Center (private) and Communicare Haven House / Region IV (Medicaid). Southern Mississippi residents are well-served by Pine Grove and Clearview Recovery Center.

Get Help Today

If you have private insurance and are ready to begin detox in Mississippi, Oxford Treatment Center offers same-day admissions when clinically appropriate. Insurance verification is free and confidential.

Verify your insurance online → or call 662-638-0015