Cychlorphine Addiction Treatment in the Mid-South
East Tennessee is at the center of the country’s largest known cluster of cychlorphine deaths. Cychlorphine is a new synthetic opioid that may be about 10 times more potent than fentanyl.1 It has also been detected in Mississippi and neighboring states.2 If you or someone you love is using opioids or street pills anywhere in the region, cychlorphine may already be in the supply. Oxford Treatment Center in Etta, Mississippi, offers medical detox and rehab for opioid addiction.
Cychlorphine in Tennessee and the Mid-South
- East Tennessee: The Knox County Regional Forensic Center linked cychlorphine to 41 overdose deaths between July 2025 and February 2026.3 Officials have warned the true number may be higher, because routine testing doesn’t detect the drug.3
- Tennessee is one of the three states with the highest prevalence nationwide, along with Ohio and Texas.3
- Mississippi, Kentucky, Arkansas, and Louisiana are among the states where a national toxicology lab has detected cychlorphine in patient samples.2
- Alabama, Arkansas, Louisiana, and Tennessee are among the 19 states where DEA crime labs have reported cychlorphine.4
- Kentucky lawmakers introduced a bill in 2026 to control cychlorphine at the state level.4
Cychlorphine has been found mixed into fentanyl, counterfeit pills, methamphetamine, and street benzodiazepines.3,4 Many people who overdose never knew they took it.
Why Professional Treatment Matters
You can’t see, smell, or test for cychlorphine at home. Fentanyl test strips don’t detect it, and neither do routine hospital urine screens.3 When it’s mixed with other drugs, overdose risk rises sharply, and so does the complexity of withdrawal.
If Someone Overdoses
Call 911 immediately and give naloxone (Narcan). If there’s no response in 2–3 minutes, give another dose. Cychlorphine may require several doses.5 Naloxone is available without a prescription at pharmacies in Mississippi and Tennessee.
Call [PHONE] 24/7 or check your insurance coverage.